PO-0408 Causes And Outcome Of Neonatal Convulsions

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Febrile Convulsions in Children: Demographic Features, Causes and Seasonal Pattern

Background and Objectives: Febrile convulsion (FC) is the most common seizure disorder in childhood period. Some studies have suggested association between seasons and occurrence of FC. This study was designed to determine demographic features, causes and seasonal variations in cases with FC. Method: In this descriptive, cross sectional study, 282 children 6- 60 months with FC were admitted to ...

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Benign familial neonatal convulsions.

Benign familial neonatal convulsions are a rare genetic seizure disorder inherited as an autosomal dominant trait. They consist of brief episodes of seizures, recurring during the first few days or weeks of life in otherwise normal babies; their prognosis is good. We report a family in which at least 12 members in three generations presented with this condition; they all had an excellent outcome.

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Phenobarbitone dosage in neonatal convulsions.

In order to find the optimal dosage schedule of phenobarbitone for neonatal convulsions, four groups of patients were studied. Twelve infants (group 1) received a mean phenobarbitone dose of 9.5 mg/kg a day given intramuscularly for 3 days followed by 5.8 mg/kg a day given intramuscularly and then orally. Six infants (group 2) received a mean intravenous loading dose of 9.5 mg/kg followed by 6....

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Significance of hypocalcaemia in neonatal convulsions.

For many years birth trauma has been stated to be the commonest cause of neonatal convulsions; there have, however, been few prospective studies to support this view. In 1954 Burke studied 46 infants who had had convulsions in the first 2 weeks of life; in 70% of the series she found birth trauma or anoxia during birth to have been the likely cause of the fit, and over a third of the infants co...

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A reduced K+ current due to a novel mutation in KCNQ2 causes neonatal convulsions.

Benign familial neonatal convulsions (BFNC) is a rare dominantly inherited epileptic syndrome characterized by frequent brief seizures within the first days of life. The disease is caused by mutations in one of two recently identified voltage-gated potassium channel genes, KCNQ2 or KCNQ3. Here, we describe a four-generation BFNC family carrying a novel mutation within the distal, unconserved C-...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 2014

ISSN: 0003-9888,1468-2044

DOI: 10.1136/archdischild-2014-307384.1054